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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FECH
All Species:
31.21
Human Site:
Y165
Identified Species:
52.82
UniProt:
P22830
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22830
NP_000131.2
423
47862
Y165
K
Y
Y
I
G
F
R
Y
V
H
P
L
T
E
E
Chimpanzee
Pan troglodytes
Q3YA36
423
47946
Y165
K
Y
Y
I
G
F
R
Y
V
H
P
L
T
E
E
Rhesus Macaque
Macaca mulatta
XP_001085580
422
47841
Y164
K
Y
Y
I
G
F
R
Y
V
H
P
L
T
E
E
Dog
Lupus familis
XP_852936
400
45170
A150
V
H
P
L
T
E
E
A
I
E
D
M
E
R
D
Cat
Felis silvestris
Mouse
Mus musculus
P22315
420
47112
Y162
K
Y
Y
I
G
F
R
Y
V
H
P
L
T
E
E
Rat
Rattus norvegicus
NP_001101904
422
47533
Y164
K
Y
Y
I
G
F
R
Y
V
H
P
L
T
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510557
430
49042
Y172
K
Y
Y
I
G
F
R
Y
V
H
P
L
T
E
E
Chicken
Gallus gallus
O42479
402
45411
L148
G
F
R
Y
V
H
P
L
T
E
E
A
I
E
E
Frog
Xenopus laevis
O57478
411
46021
Y152
K
Y
Y
I
G
F
R
Y
V
R
P
L
T
E
A
Zebra Danio
Brachydanio rerio
NP_571706
409
46017
Y151
K
F
Y
I
G
F
R
Y
V
H
P
L
T
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9S8
384
43579
F148
K
P
E
R
V
V
L
F
S
Q
Y
P
Q
Y
S
Honey Bee
Apis mellifera
XP_393413
397
45521
E152
N
T
L
Q
K
I
E
E
D
G
V
E
H
T
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04921
512
56600
P202
V
G
M
R
Y
W
H
P
F
T
E
E
A
I
E
Baker's Yeast
Sacchar. cerevisiae
P16622
393
44578
M149
T
A
E
T
Y
K
Q
M
L
K
D
G
V
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.9
86
N.A.
88.1
88.8
N.A.
82.7
79.6
78.4
71.8
N.A.
49.1
48.2
N.A.
N.A.
Protein Similarity:
100
99
96.9
89.5
N.A.
92.6
93.1
N.A.
89.3
85.1
85.3
81.8
N.A.
64.7
66.4
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
100
13.3
86.6
93.3
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
100
100
N.A.
100
20
86.6
100
N.A.
13.3
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.2
45.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.2
62.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
0
0
0
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
15
0
0
0
8
% D
% Glu:
0
0
15
0
0
8
15
8
0
15
15
15
8
65
65
% E
% Phe:
0
15
0
0
0
58
0
8
8
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
58
0
0
0
0
8
0
8
0
0
0
% G
% His:
0
8
0
0
0
8
8
0
0
50
0
0
8
0
0
% H
% Ile:
0
0
0
58
0
8
0
0
8
0
0
0
8
8
8
% I
% Lys:
65
0
0
0
8
8
0
0
0
8
0
0
0
8
8
% K
% Leu:
0
0
8
8
0
0
8
8
8
0
0
58
0
0
0
% L
% Met:
0
0
8
0
0
0
0
8
0
0
0
8
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
8
0
0
0
8
8
0
0
58
8
0
0
0
% P
% Gln:
0
0
0
8
0
0
8
0
0
8
0
0
8
0
0
% Q
% Arg:
0
0
8
15
0
0
58
0
0
8
0
0
0
8
0
% R
% Ser:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% S
% Thr:
8
8
0
8
8
0
0
0
8
8
0
0
58
8
0
% T
% Val:
15
0
0
0
15
8
0
0
58
0
8
0
8
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
50
58
8
15
0
0
58
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _